best items to unlock isaac: repentance

), Keeps the chance at 100% even after entering and leaving the angel room, meaning the door will not close after visiting, Makes it impossible to find Devil Rooms again, unless you find a way to remove or reroll this item away, or find the Duality item, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Maggy, A sack familiar that drops a sack every 5 or 6 rooms cleared (alternates between 5 and 6), UNLOCK: Unlock this item by defeating Greedier Mode as Cain, * back in black, ac/dc, bag, brown, pouch, pocket, bulge, Gives you an extra heart container for every 25 coins you are currently holding, up to a maximum of 4 extra HP at 99 coins held, If your coin counter goes below the required amount for a heart container, you will lose it again, This item works for the Keeper, allowing him to exceed his usual 2 health containers, However, if Keeper drops to under 2 health coins as a result of Greed's Gullet, he is unable to use a HP Up to increase his health back to 2, and has to regain the lost coins to do so, UNLOCK: Unlock this item by beating Challenge #35 (Pong), *, dollar, cash, sack, bag, pouch, greeds gullet, greed gullet, Gives you a random chance while firing tears to also fire a creep shot, which deals double your tear damage and places white creep on the floor infront of you that slows enemies down if they walk through it, Unlike some similar tear effects, your luck stat does not alter the chance for this effect to activate, A creep shot is also fired in a random direction after taking damage, While firing tears you have a 5% chance to fire a void tear. Function: Replaces your attack with a swinging sword. brown, brass, copper, dads key, dad key, * boss room pool, boss room item, item room, treasure room, item room pool, lumpy, red, balls, Using the portable slot takes a coin and has a chance to give a pickup - similar to how the normal slot machines work, REPENTANCE - The delay between uses was removed, allowing you to spam-use it, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, Find it . Can be used with Placebo to generate infinite batteries, Amnesia - Hides the floor map for the rest of the current floor (same as curse of the lost). From the Sacred Heart to the Magic Mushroom and the mighty Brimstone, here are some of the best and strongest items available in The Binding Of Isaac. It leaps at enemies, dealing contact damage and firing quad shots at them for the rest of the room. The Knife Piece 1 is located in the Item Room in the mirrored area. rocks, poop) in the room and deal 200 damage to all enemies in the current room, as well as every other room for the remainder of the floor, Also opens the boss rush door after Mom's Foot, blue womb door after Mom's Heart, secret rooms and super secret rooms, Like all single-use items, this item cannot be absorbed and used multiple times by the Void item, Entering a room with an angel statue will destroy it and automatically spawn one of the Angel mini bosses, REPENTANCE - This now blows up machines, beggars and fireplaces too, Upon use, this item will fart, pushing enemies away and causing a wave of rocks to spawn that spread outwards from Isaac in a circle, dealing 10 damage per hit to any enemies caught in it, Visually this item is very similar to Butter Bean, The rock waves can destroy destructible objects, e.g. And then you have the T. Lost mega satan unlock. As Azazel they fire brimstone and as The Forgotten they use a bone club, At the beginning of all future floors, two portals will appear, that can take you to either the Boss room (Red portal), Item room (Yellow portal) or Secret room (Blue portal), After Chapter 3 (The Depths floors) only one portal will spawn, Portals disappear if you leave the starting room, Every time an enemy dies, a random familiar spawns where it was killed for the rest of the room, The familiar cannot move, but continues to do its usual abilities, Possible familiars include: Abel, Boiled Baby, Brother Bobby, Sister Maggy, Little Steven, Demon Baby, Multidimensional Baby, Freezer Baby, Rotten Baby, Harlequin Baby, Ghost Baby, Guardian Angel, Lil Brimstone, Robo-Baby and Seraphim, Every 5 seconds you become spiky for a second, becoming immune and dealing 40 contact damage to any enemies that touch you, The effect is indicated by 4 white flashes, where the item activates on the 4th flash, If timed well, can be used to enter curse rooms and open spiky chests without taking damage. Order of unlocks - Binding of Isaac: Rebirth Wiki Community External Communities Wiki in: Modified in Afterbirth, Modified in Afterbirth+, Modified in Repentance Order of unlocks Edit Rebirth Categories Community content is available under CC BY-NC-SA unless otherwise noted. Passive rooms with no enemies don't have a chance to spawn Red Rooms. Eden I find very fun as well due to his randomness. After reaching level 4 (and at a much lower chance before level 4), Bumbo will also continue to collect coins and drop random pickups, similar to the Bum Friend item, but can also drop pedestal items very rarely. When you take damage and the cannon breaks, you take an additional 2 full hearts of damage and gain the Anemic effect for the room. Cannot be rerolled by 4-pip dice rooms and Spindown Dice, Clearing a room will spawn an extra reward, however only one can be picked up - the other one will disappear, UNLOCK: Unlock this item by defeating the The Beast as Isaac, Every half red heart you pick up gives a small but permanent stat increase, Randomly picks between +0.10 Damage Up, +0.05 Tears Up, +0.15 Range Up, +0.02 Speed Up, +0.1 Luck Up, +0.02 Shot Speed Up per half red heart, UNLOCK: Unlock this item by defeating The Beast as Magdalene, This item causes Devil deals to cost money instead of hearts, and shop items to cost hearts instead of money, Shop items cost heart containers, and pickups have spikes around them, The Devil deal conversion rate is 1 heart container to 15 coins, Devil deal items can be on discount similar to the shop, making it 1 heart container = 7 coins instead, UNLOCK: Unlock this item by defeating The Beast as Cain, Every time you enter a devil room and choose not to take an item, you get +1 Damage Up upon entering the next floor, The effect is shown via a cross above Isaac's head. Related: How to unlock Downpour in Binding of Isaac Repentance. Get hit by one enemy that does damage and you die. It will attempt to hide behind you when shooting. 8 coins = Slot Machine, While playing as Tainted Cain you get a visual interface to see what items are in the bag, allowing you to see what item will be created and swap out specific consumables, Has other uses - Will deal 3 damage to enemies it hits, and can be used to quickly push bombs and objects across rooms, Tainted Cain starts with this item, but can be used by any character after unlocking it and finding it in the item room, Cannot be used to craft another Bag of Crafting, UNLOCK: Unlock this item by defeating Delirium as Tainted Cain, While holding flip, a ghost item will appear behind item pedestals upon entering Item Rooms and Shop that cannot be interacted with, When activated, all real items in the room will be swapped with the ghost items behind them, The ghost item stays there even if you take the regular item, allowing you to use Flip to get both of them, Does nothing with item pedestals that don't have a ghost item behind them, When playing as Tainted Lazarus, activating Flip also changes you between Lazarus and Dead Lazarus, Tainted Lazarus starts with this item, but can be used by any character after unlocking it and finding it in the item room, UNLOCK: Unlock this item by defeating Delirium as Tainted Lazarus, When used, gives you an orbital flame which represents another random passive item in the game. After which, the only way to access an Angel Room is via the Sacrifice Room, * curse room pool, red chest pool, red chest item pool, golden chest pool, gold chest pool, devil pool, devil room pool, devil deal, brown, horns, When depleted, Black Hearts deal 40 damage to the entire room, in a Necronomicon style effect, * curse room pool, demon beggar pool, demon judgement pool, devil beggar pool, devil pool, Eden: most of Eden's unlocks are quite meh, but the fact you get Blank Card makes him worth doing. chalice, indiana jones, * angel room pool, god room pool, angel room item, bird, white, Every time you use this item it deals 40 damage to all enemies in the room and Isaac also takes damage, The first use per room takes 1 full heart, then 0.5 hearts per use after that, Shields and invincibility effects do not prevent damage when using this item, Using with Isaac's Heart previously prevented you from taking damage, however in Repentance this was fixed, Using this item as The Lost will instantly kill him, even if you have Holy Mantle active, UNLOCK: Unlock this item by beating Satan with Samson, * item room, treasure room, item room pool, razor, straight, edge, barber, bloody, brown, silver, Follows behind Isaac and can be swung back and forth, dealing 5 contact damage per tick to anything it hits, Every time the hairball kills an enemy, it grows in size allowing it to deal more damage, This is one of the items which allows you to transform into Guppy, Moving to a new floor decreases the size of the hairball, * devil pool, devil room pool, devil deal, grey, brown, pile, guppys hairball, guppy hairball, A familiar that mirrors the player's movements and shoots tears directly at Isaac, Abel's tears do 3.5 damage, unless playing as Cain in which case they do 5, REPENTANCE - Abel now has an increased rate of fire, and will mirror to the other side of the room, even if it's off screen. To do so, you'll have to have unlocked Cain, defeated Mother (on any character), and unlocked the ascent path. The floor generation can fail and cause the guaranteed Planetarium to not spawn sometimes. To unlock challenge 4: 'Darkness Falls' you need to defeat Isaac while playing as Eve. It returns after a room has been cleared, UNLOCK: Unlock this item by beating Greed Mode with Eden, Item Pool: Item Room, Secret Room, Greed Mode Shop, *, red, yellow, green, white, square, rectangle, When used, the D8 rerolls all of your stats, Will only effect your damage, tears, range and speed stats, Each stat is given a multiplier that applies after all other adjustments, UNLOCK: Unlock this item by beating Challenge #28 (Pride Day), * dice, pip, die, black, grey, gray, pyramid, triangle, Purity will boost one of Isaac's stats depending on the colour of the aura around him, When you take damage, the aura will be removed and replaced with another random one when you enter the next room, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Maggy, Item Pool: Item Room, Angel Room, Greed Mode Item Room, Greed Mode Angel Room, Adds a chance for a black ring to spawn around killed enemies, dealing damage to others that touch it, The ring damage scales with your tear damage, The change for a ring to spawn scales with your lucky stat, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Eve, Item Pool: Devil Room, Curse Room, Greed Mode Devil Room, *, grey, gray, silver, metal grabber, hand, robot, When Isaac has no red hearts, this item gives Isaac the ability to fly. REPENTANCE - Dead Sea Scrolls now displays the name of the given effect, and can no longer give Kamikaze. The only way to remove it is via having a second trinket slot (Mom's Purse, Belly Button) or absorbing it (Marbles, Smelter, Gulp! This effect also works on Delirium if it is currently transformed into The Haunt while below half health, UNLOCK: Unlock this item by defeating Greedier mode as Bethany, Identified all pills on pickup, and converts them to their worse counterparts (e.g. Supper = +0.5 tears, +1 luck. grey, gray, green, mouth, bobs rotten head, bob rotten head, Teleports Isaac to a random location on the map, Can't be used to teleport to the I AM ERROR room, REPENTANCE - Teleport! See the Broken Shovel / Mom's Shovel items for more information on how to unlock, Rotten Hearts fill up a whole container the same as normal red hearts, or the rightmost heart if you're at full health, Every time you clear a room, you'll spawn 2 Blue Flies for each Rotten Heart you currently have, UNLOCK: Unlock this by entering the Corpse floor for the first time, Spawns 2-3 pills, black/bone hearts and/or bombs when picked up, Can spawn in place of a regular sack, including in Shops for 7c, Only one heart can spawn per sack as a maximum, UNLOCK: Unlock this by defeating Mega Satan as Tainted Judas, 48 Hour Energy - Fully recharges your active item and drops 1-2 battery pickups. uses as his main mechanic, Killing or damaging enemies spawns various poops, which add to his collection. After killing a 15 enemies, Blood Puppy transforms into an aggressive version that will also attack Isaac by charging at him. Only contact poison has this effect - poison from tears doesn't work, UNLOCK: Unlock this item by beating Satan with Lilith, *, green, lips, kiss, drip, drop, serpents kiss, serpent kiss, Isaac will now fire tears automatically directed at a red target on the ground which is controlled by the player, This allows for a full 360 degree tear firing radius, Can be overridden by other tear modifiers such as Mom's Knife or Brimstone, Every time you leave the room this effect turns off until you press a shoot button again, Tears are replaced with the ability to charge and fire a laser ring that travels across the room, The size of the ring will depend on how long you charge it, The laser ring does damage scaling based on charge, from 25% at minimum to 100% at max, Rings have infinite range and travel until they hit a wall, Multiple Tech X stacks - every one taken adds another laser ring (doesn't affect your fire rate), * tech 10, tech ten, donut laser rings, vr, headset, visor, Allows you to create one brown tunnel and one blue tunnel in the floor, that can be used to teleport between wherever you placed each one, This item will let you port out of the devil room but not back into it, Very useful in the boss rush and challenge rooms, *, scalpel, red, silver, white, grey, gray, metal, knife, cut, Isaac's tears now travel directly forwards following a beam of light, but will also move sideways based on your player movement, Allows for more accurate correction when firing tears, as their direction can be controlled even after they have been fired, If you switch the direction in which you are firing tears, the beam of light and all your tears will also be transported to the new direction, Tears now have a random chance to apply a shrinking effect, causing enemies to shrink in size for 5 seconds and also run away from Isaac, Shrunk enemies can be crushed and killed by walking over them, After firing tears for 3 seconds, a red cross appears on Isaac's head that, upon releasing the fire button, creates a black ring which deals a lot of damage to any enemies inside it, The ring deals damage equal to your tear damage rapidly to any enemies in contact with it, for a total of 30 ticks of damage, You have to keep the fire button held down for the full 3 seconds to cause this effect, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Azazel, In addition to tears, Isaac now holds a spear infront of him which deals damage equal to 2 times your tear damage. 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