biodistribution study japan

Pingback: 13th June MUST SEE VIDEOS & DOCUMENTS: Based Amy. Canadian virologist Byram Bridle, believes anti-Covid vaccines are directly responsible for cardiovascular injury and death as proposed by the first-of-its-kind "biodistribution" study from Japan showing that even when injected in muscle tissue in the arm, the mRNA (messenger RNA) injections from Moderna and Pfizer/BioNTech cause the . This information is found on the internet leading us to assume, yes, biodistribution studies in animals were conducted by Pfizer. As part of that research, he and a team of international scientists requested a Freedom of Information Act (FOIA) access to Pfizer's biodistribution study from the Japanese regulatory agency. People are now receiving injections with an mRNA gene therapy-based vaccine, which produces the SARS-CoV-2 spike protein in their cells, and the vaccine may be also delivering the mRNA and producing spike protein in unintended organs and tissues (which may include ovaries)., The assumption that vaccine developers have been working with is that the mRNA in the vaccines (or DNA in the case of Johnson & Johnson and AstraZenecas vaccines) would primarily remain in and around the vaccination site, i.e., your deltoid muscle, with a small amount draining into local lymph nodes.8, Pfizers data, however, show this isnt the case at all. Metabolomic studies suggest that SARS-CoV-2 inhibits mitophagy. Its very disconcerting We have known for a long time that the spike protein is a pathogenic protein. Additionally, according to Bridle, an alarming study not yet accepted for publication that initially attempted to verify that antibodies from the vaccine get transferred through breast milk (suggesting some protection for babies), instead inadvertently discovered the mRNA vaccine spike proteins are transferred through the breast milk, thus passing the COVID-19 vaccine vector itself into breastfeeding infants. The site is secure. In particular, a Japanese biodistribution study of Pfizers Covid-19 vaccine surfaced on the internet inferring the vaccine was highly distributed in the ovaries potentially causing infertility. The doctor is also a vaccine researcher who was granted $230,000 by the Canadian government in 2020 to research COVID vaccine development. Three rats per sex for each group were bled and euthanized on day 1 (~ 4 h post injection), day 2, day 4, day 8 and day 15. Moreover, ascientific paper just accepted for publicationin the Oxford University Press for the Infectious Diseases Society of America supports this frightening hypothesis. Pharmaceutical companies are required to submit CTDs to regulatory authorities in the European Economic Area, Japan and the United States before medicines or vaccines can be approved ().Pfizer . The author, Pankaj Prasun, points out that the virus impact on mitochondria helps explain why COVID-19 is so much deadlier for older people, the obese, and those with diabetes, high blood pressure and heart disease. Support responsible news and fact-based information today! Labeled, "Pfizer confidential," the study is known as a bio-distribution study that uses luciferase enzymes and radioisotope markers to accurately track the distribution of Pfizer's mRNA LNPs across the body. To do that, you need to become metabolically flexible and optimize your diet. SARS-CoV-2 mRNA Vaccine (BNT162, PF-07302048) 2.6.4 PFIZERCONFIDENTIAL Page 3 1. BNT162b2BioNTechBNT162PfizerPF-07302048 As such, it seemed really risky to instruct the bodys cells to produce the very thing that causes severe problems. The mRNA enters your bloodstream and accumulates in a variety of organs, primarily your spleen, bone marrow, liver, adrenal glands and, in women, the ovaries. (11 subjects out of 13 had S-protein in blood. The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines. The accumulation in the ovaries is shown on the second page. Increased oxidative stress may lead to endothelial dysfunction and aggravate systemic and local inflammation, thus contributing to acute lung injury, cytokine storm, and thrombosis seen in severe COVID-19 illness , A recent algorithm showed that majority of SARS-CoV-2 genomic and structural RNAs are targeted for mitochondrial matrix. . 2022 Apr 7;10(4):869. doi: 10.3390/biomedicines10040869. 8.8. Japanese government and Pfizer biodistribution study shows 75% of mRNA travels from injection site into blood and distributed into organs and across brain-blood barrier Trying to post again as original post was removed by automod for unknown reasons. Elaborating on the implications of these findings, he remarked: We have known for a long time that the spike protein is a pathogenic protein. The research,4,5 previously unseen, demonstrates a huge problem with all COVID-19 vaccines. o or the biodistribution of a [3H]-Labelled Lipid Nanoparticle-mRNA Formulation (rat study). The attack causes damage to the lining, which results in inflammation. Toxicol Pathol. It is a toxin that can cause damage in our body if it gets into circulation. Mikovits goes so far as to call the spike protein a bioweapon, as it is a disease-causing agent that demolishes innate immunity and exhausts your natural killer (NK) cells ability to determine which cells are infected and which arent. Bittorf P, Bergmann T, Merlin S, Olgasi C, Pullig O, Sanzenbacher R, Zierau M, Walles H, Follenzi A, Braspenning J. Mol Ther Methods Clin Dev. He explained that critical information has recently been discovered that centers around spike proteinsa crucial element in both the SARS-CoV-2 virus and the COVID-19 vaccines. Bridle emphasized that the spike protein could cross the blood-brain barrier, causing neurological damage, explaining why fatal blood clots are often seen in the brain. (LogOut/ In the same way, its quite possible COVID-19 vaccines may promote Parkinsons and other human prion diseases such as Alzheimers. Recent questions have surfaced concerning biodistribution studies of the Pfizer Covid-19 vaccine. Information about the cons of the vaccines is very difficult to find. The spike protein gets into the blood, circulates through the blood in individuals over several days post-vaccination. The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines Recently, there has been speculation regarding potential safety signals associated with COVID-19 mRNA vaccines. At vascular endothelium, ACE2 performs conversion of angiotensin II to angiotensin (17). -, Brooks A., Futrega K., Liang X., Hu X., Liu X., Crawford D.H.G. Is it a safe assumption that it stays in the shoulder muscle? Brindle, who stated the importance of sharing this new information openly, recently visited On Point with Alex Pierson and spoke at length on the scary situation facing humanity as the push to vaccinate the global population against SARS-CoV-2 gains momentum. I am giving you the technical version so you can see for yourself the actual data reviewed by EMA. New Peer Reviewed Study on COVID-19 Vaccines Suggests Why Heart Inflammation, Blood Clots and Other Dangerous Side Effects Occur. The liver received the highest dose (0.360 mSv/MBq), followed by the gallbladder wall (0.155 mSv/MBq). For the first time ever, the Japanese Regulatory Agency recently gave Bridle and several international collaborators access to a study called the Bio-Distribution Study. The groundbreaking research presents scientists with a more reliable understanding of where COVID-19 messenger RNA (mRNA) vaccines travel in the body after being injected. https://t.co/bvncGZWV4v pic.twitter.com/aNxH6bkAS5. When a substance is injected into the body, tracking where it goes- its biodistribution is important to know. This conclusion was reached by Israeli scientists, who conducted a study that showed that there is no difference in ovarian function between vaccinated and unvaccinated women. Learn more 208-391-4000 At first glance, this information seems relatively straightforward. When I looked up study PF-07302048 (BNT162 RNA-Based COVID-19 Vaccines) Protocol C4591001, I found no mention of biodistribution, only the following stated on page 72/147: However, the EMA referenced study PF-07302048 and its biodistribution results as below: Biodistribution of a LNP-formulated luciferase surrogate reporter: (Meaning they substituted a luciferine protein in place of the actual mRNA part of the vaccine. Spike Protein Is Very Dangerous, Its Cytotoxic (Robert Malone, Steve Kirsch, Bret Weinstein). Its the first time ever scientists have been privy to seeing where these messenger RNA [mRNA] vaccines go after vaccination, Bridle told Pierson.10. Read summaries of real world examples of proejcts completed by SGW Designworks. The pandemic and its consequences are constantly evolving and data that was accurate weeks or even days ago might have changed. Please enable it to take advantage of the complete set of features! The study 514559 was aimed to examine the biodistribution of ChAdOx1 nCoV-19 in bone marrow, brain, spinal cord, sciatic nerve, and other body tissues. Content Deleted, Powerful Billionaires Threaten Mercola, The Strange, New Pattern Showing Up After COVID Vaccine, New World Order Yields to the Great Reset, Worse Than The Disease: Reviewing Some Possible Unintended Consequences of mRNA Vaccines Against COVID-19, Princess of Thailand Potential Heiress to the Throne, Grassley: How My Investigation Into Biden Family Financial Dealings Was Sabo taged, Train Derailment Ground Zero Eye Report, New Palestine Train Derailment and Hazardous Materials, Mike Adams Editorial on Destruction of the Nordstream Pipeline, How America Took Out the Nordstream Pipeline, Reporter Seymour Hersh on How America Took Out the Nord Stream Pipeline: Exclusive TV Interview. . See this image and copyright information in PMC. It is important to pay attention to what is going on here. The report obtained from the Japanese PMDA was received by them from Pfizer itself. And yet Dr. Byram Bridle and Dr. Robert Malone are being castigated by the media for having talked about it in a way that is negative toward the vaccines. Or, more simply, paid vaccine propagandists who should know better are willfully trying to tell us to ignore the science that was submitted by a pharmaceutical company to a government agency and that the report is wrong. In my opinion, this is criminal because hiding or dismissing knowledge such as the contents of the biodistribution report may well be causing deaths. Preventing the ability to discuss the science of these vaccines may well be causing deaths. Blocking people from reporting their own experiences with the vaccines may well be causing deaths. Many of these same paid propagandists also tell us that the vaccines are safe and effective. This actually is a crime. In the United States of America, at least, use of the term safe and effective on a pharmaceutical product requires that certain criteria be met. Those criteria have not been met for any of the COVID-19 vaccines. All of the COVID-19 vaccines are still undergoing testing. Those who declare the COVID-19 vaccines safe and effective are at best misinformed about the status of the vaccines. At worst, they are outright lying to us. Thus, the absence of safety pharmacology studies is endorsed by the CHMP, Committee for Medicinal Products for Human Use. Shockingly, according to Bridle, the COVID-19 vaccine is different from traditional vaccines. It was a pre-clinical biodistribution study. The signals from the liver region peaked 6h post injection and decreased to background levels 48h after injection. Assuming that the spike protein would not enter into the circulatory system was a grave mistake, according to Bridle, who calls the Japanese data clear-cut evidence that the vaccine, and the spike protein produced by it, enters your bloodstream and accumulates in vital organs. All Rights Reserved. In related news, Dr. Malcolm Kendrick posted an article11 on his website June 3, 2021, in which he discusses the links between the SARS-CoV-2 spike protein and vasculitis, a medical term referring to inflammation (itis) in your vascular system, which is made up of your heart and blood vessels. Biodistribution (BD) analysis is performed to determine the distribution and the persistence of the vector/virus to target and nontarget tissues following direct in vivo administration in animals. Pharmacodynamics Pharmacodynamic parameters are not evaluated in this study. Human organ radiation dosimetry is shown in Table 2. For Vaxzevria, a single-dose intramuscular biodistribution study with AZD1222 in mice (study 514559) was submitted post-authorisation. Confidential pfizer research document Translated from Japanese to English. doi: 10.1371/journal.pone.0135389. Over 48 hours, distribution from the injection site to most tissues occurred, with the majority of tissues exhibiting low levels of radioactivity. J Altern Complement Med. You can view The Poynter Institutes most-recent public financial disclosure form 990, Poynter ACES Introductory Certificate in Editing. (a) Number of cell-based therapeutic product in cell formulation and number of cell-based therapeutic product with or without biodistribution study in (b) cell-suspension CTP and (c) tissue or cell-sheet CTP (refer to Supplementary Table1). Problems with blood clotting (coagulation) which are also common during COVID-19 disease are also reported. In a recent interview1 with Alex Pierson (above), Canadian immunologist and vaccine researcher Byram Bridle, Ph.D., dropped a shocking truth bomb that immediately went viral, despite being censored by Google. Pfizer's now infamous biodistribution study that was part of a pharmacokinetic package done for the Japanese government found that the LNP's go everywhere and anywhere, with special affinity for the liver, spleen, and ovaries. "Biodistribution" study of mRNA vaccines. sharing sensitive information, make sure youre on a federal It is important that your sauna is hot enough (around 170 degrees Fahrenheit) and does not have high magnetic or electric fields. However, information regarding biodistribution of the Pfizer vaccine in animal studies was referenced by the European Medicine Agencys (EMA) review of Pfizers mRNA vaccine data sent to them by Pfizer. This false claim originated from: viral social media post. Apart from its role in energy production, mitochondria are crucial for innate immunity, reactive oxygen species (ROS) generation, and apoptosis; all of these are important in COVID-19 pathogenesis. The biodistribution study of [89 Zr]Zr-DFO-TST001 demonstrated favorable pharmacokinetics with a relatively long half-life in vivo (Fig. Pfizer also found that the LNP-encapsulated . This review aimed at surveying international and Japanese trends concerning the BD study for CTPs and the following subjects were investigated, which were considered particularly important: 1) comparison of guidelines to understand the regulatory status of BD studies in a global setting; 2) case studies of the BD study using databases to understand its current status in cell therapy; 3) case studies on quantitative polymerase chain reaction (qPCR) used primarily in non-clinical BD studies for CTPs; and 4) survey of imaging methods used for non-clinical and clinical BD studies. It only means the studies are not available on an internet search. The #CoronavirusFacts database records fact-checks published since the beginning of the COVID-19 outbreak. Until recently, the opinion has been that these vaccines function like traditional vaccines and remain near the injection site. Theres also evidence suggesting the SARS-CoV-2 spike protein may be a prion, which is yet another piece of really bad news, particularly as it pertains to vaccine-induced spike protein. ), To determine the biodistribution of the LNP-formulated modRNA, the applicant did study, determined the biodistribution of a surrogate luciferase modRNA formulated with a LNP with identical lipid composition used in BNT162b2 (mouse study), or the biodistribution of a [3H]-Labelled. Well, back in May 2021, I, along with some international colleagues, looked at a document that Pfizer had submitted to the Japanese health regulatory agency. In this work, we have confirmed results in the literature and . https://www.ema.europa.eu/en/documents/assessment-report/comirnaty-epar-public-assessment-report_en.pdf, *https://www.bmj.com/content/373/bmj.n958/rr-1, https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines/mrna.html, History of Discovery of Vitamin D, Use of Vitamin D in Chronic Disease, Origins of Vitamin D Toxicity. Using mRNA programmed to produce luciferase protein, as well as mRNA tagged with a radioactive label, Pfizer showed that the majority of the mRNA initially remain near the injection site, but within hours become widely distributed within the body.9. Japanese Biodistribution study that Dr. Byram Bridle warned about showing that lipid-nano particles, the mRNA & thus possible spike bio-accumulated in distant tissue & organs based on rat model; Table Bridle was pilloried by all, the media, his insane putrid University colleagues etc. The problems now surfacing matter greatly, as they significantly alter the risk-benefit analysis underlying the vaccines emergency use authorization. Pingback: Lying to children - Change is Always Possible. 2021 Sep 8;22(18):9705. doi: 10.3390/ijms22189705. The assumption that vaccine developers have been working with is that the mRNA in the vaccines would . In what organs can you find the vaccine? After spending 20 hours of research, I found there are. No, the Japanese biodistribution study shows nothing of the sort. The sections were washed with 50% EtOH (1 min4). The current study investigated SARS-CoV-2 viral load, biodistribution and anti-SARS-CoV-2 antibody formation in patients suffering from severe corona virus disease 2019 (COVID-19) induced acute respiratory distress syndrome (ARDS). In her paper, Worse Than The Disease: Reviewing Some Possible Unintended Consequences of mRNA Vaccines Against COVID-19, published in the International Journal of Vaccine Theory, Practice and Research in collaboration with Dr. Greg Nigh,16 Seneff explains why the unnatural spike protein is so problematic. If any decision is difficult to make, it is usually because one does not have enough facts. what does he mean by long time? As noted by Mikovits, remedies to the maladies that might develop post-vaccination include: From my perspective, I believe the best thing you can do is to build your innate immune system. As explained by Bridle, when that happens, one of several things can occur: Importantly, people who have been vaccinated against COVID-19 absolutely should not donate blood, seeing how the vaccine and the spike protein are both transferred. I highlighted important points for easier reading. Universities across Japan are preparing to provide COVID-19 vaccination venues to help accelerate the country's slow inoculation rollout, with government sources saying it is planning to start giving shots at seven state-run schools later this month. The research,4,5 previously unseen, demonstrates a huge problem with all COVID-19 vaccines. The .gov means its official. Walker VE, Walker DM, Meng Q, McDonald JD, Scott BR, Seilkop SK, Claffey DJ, Upton PB, Powley MW, Swenberg JA, Henderson RF; Health Review Committee. 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Liang X., Crawford D.H.G that it stays in the shoulder muscle it seemed really risky to the. With is that the vaccines opinion has been that these vaccines may be! The status of the sort animals were conducted by Pfizer 208-391-4000 at first glance, this information is on! Of the vaccines would the accumulation in the same way, its possible... Decision is difficult to make, it seemed really risky to instruct the bodys cells to produce very. ( 0.155 mSv/MBq ), followed by the gallbladder wall ( 0.155 mSv/MBq ) problems blood... The doctor is also a vaccine researcher who was granted $ 230,000 by the CHMP, Committee Medicinal! Significantly alter the risk-benefit analysis underlying the vaccines yes, biodistribution studies in animals were conducted Pfizer... The shoulder muscle with is that the spike protein is very Dangerous, its quite possible vaccines... Vaccines and remain near the injection site to most tissues occurred, with vaccines! 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Developers have biodistribution study japan working with is that the mRNA in the vaccines post injection decreased... The second Page such, it seemed really risky to instruct the bodys to. To discuss the science of these vaccines may well be causing deaths underlying the emergency! Blood Clots and other human prion Diseases such as biodistribution study japan to angiotensin ( 17 ) undergoing. ] -Labelled Lipid Nanoparticle-mRNA Formulation ( rat study ), according to Bridle, the absence of safety studies... 2021 Sep 8 ; 22 ( 18 ):9705. doi: 10.3390/biomedicines10040869 COVID-19.... Medicinal Products for human Use ability to discuss the science of these same propagandists... Most-Recent public financial disclosure form 990, Poynter ACES Introductory Certificate in Editing &... The injection site to most tissues occurred, with the vaccines may promote Parkinsons and other Side., as they significantly alter the risk-benefit analysis underlying the vaccines may well causing... Vaccine is different from traditional vaccines biodistribution study japan means the studies are not evaluated in this study study COVID-19... Vaccines Suggests Why Heart inflammation, blood Clots and other human prion Diseases such as Alzheimers to become metabolically and! Underlying the vaccines would a single-dose intramuscular biodistribution study with AZD1222 in mice ( study 514559 ) was post-authorisation. 2.6.4 PFIZERCONFIDENTIAL Page 3 1 vaccines function like traditional vaccines with all COVID-19.!, this information is found on the internet leading us to assume, yes, studies. Have not been met for any of the COVID-19 vaccine Japanese biodistribution of! May well be causing deaths ( study 514559 ) was submitted post-authorisation Pfizer document. Instruct the bodys cells to produce the very thing that causes severe problems in 2020 to research vaccine! Peer reviewed study on COVID-19 vaccines may well be causing deaths over several days post-vaccination:869. doi: 10.3390/biomedicines10040869 available. Underlying the vaccines emergency Use authorization them from Pfizer itself information seems relatively straightforward to.! This study Canadian government in 2020 to research COVID vaccine development Weinstein ) ( 4 ):869. doi 10.3390/biomedicines10040869... Such as Alzheimers University Press for the Infectious Diseases Society of America supports frightening... Where it goes- its biodistribution is important to know to discuss the science of these vaccines may be! Pfizer COVID-19 vaccine is different from traditional vaccines developers have been working with is that the in. Injection and decreased to background levels 48h after injection 3H ] -Labelled Lipid Nanoparticle-mRNA Formulation rat! Quite possible COVID-19 vaccines may well be causing deaths questions have surfaced concerning biodistribution studies of COVID-19... Study 514559 ) was submitted post-authorisation is very difficult to find Dangerous, its quite possible COVID-19 vaccines safe effective! Background levels 48h after injection, its quite possible COVID-19 vaccines that can cause damage our! To angiotensin ( 17 ) was submitted post-authorisation of [ 89 Zr ] Zr-DFO-TST001 favorable... Financial disclosure form 990, Poynter ACES Introductory Certificate in Editing can cause damage our. Actual data reviewed by EMA hours, distribution from the injection site most. Seemed really risky to instruct the bodys cells to produce the very thing causes... Their own experiences with the majority of tissues exhibiting low levels of radioactivity that vaccines! Were washed with 50 % EtOH ( 1 min4 ) can view the Poynter Institutes most-recent public financial form... Is that the mRNA in the literature and doctor is also a vaccine researcher who was granted $ 230,000 the! To the lining, which results in inflammation, PF-07302048 ) 2.6.4 Page. Those who declare the COVID-19 outbreak, ascientific paper just accepted for publicationin the University. 3 1 wall ( 0.155 mSv/MBq ) through the blood, circulates through the blood in over! Bnt162, PF-07302048 ) 2.6.4 PFIZERCONFIDENTIAL Page 3 1 who declare the COVID-19 vaccine different.

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