what is sterile diluent for dogs

What experience do you need to become a teacher? See full prescribing information for HUMULIN N. HUMULIN N (insulin isophane human) injectable suspension, for subcutaneous use Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Veterinary Use Only CONTAINS: Contains no antimicrobial or other added substance. This solution has a pH of 2 to 3.5 and is recommended for deep intramuscular injection in the dog and cat and STERILE DILUENT- diluent injection, solution Eli Lilly and Company-----HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use HUMULIN N safely and effectively. This process of rehydrating the vaccine is known as "reconstitution". Diluting; denoting that which dilutes. Healthy dogs should receive 2 doses administered 34 weeks apart. Ok, so youve been to the vet and theyve given you a bottle of sterile diluent and a vial of vaccinations for your dog. Excludes Vanguard Feline FIP and Vanguard Rabies products. Updated: 2023-02-28. Using a sterile mixing syringe with a 38 mm 18-gauge (18G X 1") needle, draw up a small amount of diluent from the bag. The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". To make thinner by adding solvent to a solution; especially by adding water. 135,136 A new, sterile syringe and . ACTH stimulation tests are also used to monitor dogs with Cushings disease who are being treated with the drug mitotane. Blood is made up of blood cells, red blood cells and plasma. Remember the fact that the pictures in what is sterile diluent for dogs is usually downloaded and saved on a computer or cellphone. 462.239999 0] In addition, sterile diluent can be used to flush out dogs eyes and ears. Sterile Diluent for Constitution single-dose vial: NDC 73607-001-02. These drugs are given by injection as part of an ACTH stimulation test, which determines whether or not a dogs adrenal glands are functioning normally. If the diluent has a stronger eluting strength than the MP, sample peaks (especially early-eluting peaks) may be severely distorted because of solvent mismatch, which may cause problems in impurity determinations. 25 x 1 ml single dose vials with sterile diluent and nasal applicators Ingredients: Canine parainfluenza, modified . The diluent for HIBERIX is a sterile saline solution (0.9% sodium chloride) supplied in prefilled TIP-LOK syringes.. How do you reconstitute hiberix? Diluent for reconstitution of sterile injectable products, Federal (USA) law restricts this drug to use by or on the order of a licensed. What was your actual dilution factor? Diluent Sterile (chemical formula: H2O) is a transparent fluid which forms the worlds streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms. Antonyms for (adjective) sterile Main entry: unfertile, sterile, infertile Definition: incapable of reproducing Usage: an infertile couple Main entry: aseptic, sterile Definition: free of or using methods to keep free of pathological microorganisms Usage: a sterile operating area; aseptic surgical instruments; aseptic surgical techniques. Gently swirl; do not shake. Attention! 607.199999 0] A bivalent, inactivated vaccine for the immunization of dogs against leptospirosis caused by Leptospira canicola and Leptospira icterohaemorrhagiae. The cookie is used to store the user consent for the cookies in the category "Other. Diluent for reconstitution of sterile injectable products. A hypertonic saline solution in fluid therapy improves cardiovascular function, stimulated myocardial contractions, and peripheral blood flow, which is needed in shock patients. Alternatively, you can sanitize many hard toys by running them through the dishwasher, and you don't even need to add soap. %PDF-1.4 To give an intramuscular (IM) injection, the skin over the injection site should be sterily prepped with alcohol or another antiseptic solution. Mixing with certain medicines that are given by injection. This product has been shown to be effective for vaccination of healthy dogs 6 weeks of age or older against canine distemper virus, canine adenovirus type 1 (hepatitis), canine adenovirus type 2 (respiratory disease), canine parainfluenza virus and canine parvovirus. If you continue to use this site we will assume that you are happy with it. I do not offer this information as a professional or as a prescription, as one must be a licensed veterinarian to do that legally. Diluents are used to increase the size of the dosage form. Draw the contents from the vaccine ampoule (and tip) into the syringe and swirl gently. A transfusion may also be necessary when anemic patients misplace their own red blood cells- a condition called red cell loss or anemias, respectively. Its a question that has baffled dog owners for centuries. The solution should be homogenous, clear and free from particles. 7 What is the difference in sterile water and sterile saline? Are Caucasian Shepherd good for first time owners. Then 0.1 ml of dilution tube #1 was added to and thoroughly mixed with 9.9 ml of sterile water. << During an operation, the surgeon would need to stop the bleeding or coagulation of the body parts to be operated on so that he can perform the surgery without any resistance. Two 50 mg vials will be required for dogs weighing >20 kg and 40 kg and 3 vials will be required for dogs >40 kg and 60 kg. No antimicrobial agent or other substance has been added. Estradiol is a naturally occurring estrogen. 60 0] It may be more useful in injection form or sometimes in tablet form. The choice of diluent is certainly case-by-case, but in this example of a water-soluble active pharmaceutical ingredient, the method developer can improve the odds against impurity solubility issues by incorporating 1050% acetonitrile or methanol into the sample diluent. Sterile water and normal saline solution. When prepared correctly, saline solution is equivalent to distilled water. According to a study in the Journal of the American Veterinary Medical Association, that wont be necessary. It is recomended to use sterile saline without perservative. Each 100 ml of Hypertonic Saline Solution contains 7.2 g Sodium Chloride. /SA true STERILE DILUENT (sterile water for injection) Diluent for reconstitution of sterile injectable products CAUTION: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Diluent can come from refineries or natural gas production wells. It is commonly used in veterinary medicine, and is also used in human medicine. They are sometimes misunderstood as being synonyms; however, solvents are liquids that dissolve other substances called solutes while diluents are liquids that dilute the concentrations of other liquids. This product has been shown to be effective for vaccination of healthy dogs 6 weeks of age or older against canine distemper virus, canine adenovirus type 1 (hepatitis), canine adenovirus type 2 (respiratory disease), canine parainfluenza virus and canine parvovirus. /CSp /DeviceRGB /Annots 20 0 R The answer is simple: theyre trying to commit suicide. If youre reading this, then perhaps youre also wondering why your dog is afraid of the air fryer. . We use cookies to ensure that we give you the best experience on our website. As a chemical compound, a Diluent Sterile molecule contains one oxygen and two hydrogen atoms that are connected by covalent bonds. The vaccine is administered in a dog's buccal cavity, and Merial says studies suggest it offers dogs a "robust immune response after a single dose." Frank Capella, co-owner of Village Veterinary Hospital in Canastota, New . Kendall Sterile Saline Irrigation Solution is a sterile fluid that is specifically designed for medical use. Blood also helps with blood clotting, blood pressure and clotting time. Insert the needle into the vial of vaccine and turn it upside down. Mix 1.8 mL of the diluent with the thawed vaccine. Set id: 8218b086-0cd2-487a-bf2a-051b10b89f5f. Keep this product, as well as syringes and needles, out of the reach of children and away from pets. This product cannot be mixed with all medicines. What are the two most common diluents used for reconstituting sterile powder drug vials? /Type /Page Draw back on the syringe to remove all of the sterile diluent. * Never replace a vaccine diluent with water for injection, and never inject an oral vaccine or a diluent used to reconstitute an oral vaccine. Estrogens may also be given to female dogs to encourage them to come into heat or to intact male dogs to treat benign prostatic hypertrophy (BPH). Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. Antidote: may all be indicated depending on the nature and severity of the reaction. [0 /XYZ 69.5999999 The definition of a diluent in immunochemistry is a liquid solution that reduces the potency of another substance or liquid. However, in the published literature, rats and mice administered oral or intraperitoneal artesunate as a single . Sterile Diluent Sterile for Irrigation USP is indicated for use as an irrigating fluid or pharmaceutic aid. Sterile Water for Irrigation that has been warmed must not be returned to storage. The needle should be inserted at a 90 degree angle to the skin and only penetrates through the skin and subcutaneous tissue- never enter into muscle tissue. The diluent (solvent, liquid) commonly used for reconstitution is sterile water or sterile normal saline solution, prepared for injection. Your veterinarian may prescribe a sterile diluent for your dog if they are suffering from dehydration or if they need to take medication that needs to be diluted. The pH is 5.5 (5.0 to 7.0). Every year, thousands, Welcome to my blog! Treat for bacterial pneumonia for at least seven days! Dosage (Posology) and method of administration. No antimicrobial or other substance has been added. Fill a large pot with warm water and place it on the stove. endobj like you might be at this time in search of content articles about what is sterile diluent for dogs. Sterile water is not a balanced solution and may burn upon injection. /CA 1.0 The cookie is used to store the user consent for the cookies in the category "Performance". Refrigerate solution and use within one month. Plus, it contains the components found in tears in just the right amounts. The need for this booster has not been established. * Slowly inject diluent to prevent excess foaming or bubbling. https://www.drugs.com/search.php?searchterm=diluent-sterile, https://pubmed.ncbi.nlm.nih.gov/?term=diluent-sterile. It does not need to be at the same temperature, but freezing must be avoided so the vial does not crack. A diluent should contain harmful products in the smallest possible amount, and in this sense contain less than 12% of aromatics, be free from ether-ethylglycol, acetates, ethylglycolacetate, methylglycolacetate (also called ethoxyethylacetate and methoxyethylacetate), ultimately replaced by propyl derivatives: . . A p p r o v a l : 1 9 8 2) S . Contains no antimicrobial or other added substance. Healthy dogs should receive 2 doses administered 3-4 weeks apart. These vaccines include Nimenrix, Priorix, Infanrix Hexa, Priorix Tetra, Proquad, MMRII, Varilrix, Varivax. Live Chat. 14 0 obj 2 Does sterile diluent need to be refrigerated? Product Information for Veterinary Healthcare Professionals Diluent used for the reconstitution of freeze-dried small animal Nobivac vaccines for dogs and cats which include instructions to be reconstituted with Nobivac Solvent. Hopefully, the article about what is sterile diluent for dogs above meets your needs, everyone has a better idea, please leave a comment below, all your suggestions help us create better and better articles for everyone. What is sterile diluent for dogs To ensure that the medications are properly mixed and distributed, sterile diluent is a type of liquid used to dilute or dissolve medications prior to injection. Diluent Sterile is a sterile solution used to mix and dilute other medicines. 9 0 obj The main drawback of using sterile diluent for dogs is that it can be expensive. But can they really digest it? Androgens have a variety of uses such as treating hormone-responsive urinary incontinence in male dogs, suppression of heat cycles and alleviation of false pregnancies in female dogs, and as part of the therapy for some types of immune-mediated blood disorders. A vaccine diluent may be sensitive to heat or freezing, and may require transportation and storage in the cold chain. The addition of 5 mL diluent produces a solution containing the equivalent of 50 mg tiletamine base, 50 mg zolazepam base and 57.7 mg mannitol per milliliter. Place the antlers in the water, ensuring that they are fully submerged. Chronic Health Effects No chronic health effects known. The diluent must be shipped and distributed at the same time and in the same quantity as the vaccine vials. Diluent Bacteriostatic Sodium Chloride 0.9% Injection Multiple Dose Vial 30 mL Bacteriostatic 0.9% Sodium Chloride Injection, USP is a sterile, nonpy This preparation is designed for parenteral use only after addition of While there is NO vaccine for Bordetella that will provide sterile immunity, vaccination still provides some protection from infection, and vaccinated dogs are expected to develop milder clinical signs if they do become infected. After reconstitution of the freeze-dried fraction with the diluent fraction, administer one dose of CANIGEN DHP by the subcutaneous or intramuscular route for primary vaccination in puppies at 6 weeks of age. This website uses cookies to improve your experience while you navigate through the website. counts or morphology were observed in rats and dogs following 28 days of repeated dosing with intravenously administered artesunate. It usually containsWater for Injection (WFI) and may also contain an isotonic agent such asSodium Chloride Injection, USP or Dextrose Injection, USP. Read on to learn exactly what you are giving your dog and what problems you should watch out for. << a dilute solution of bleach. S e e f u l l p r e s c r i b i n g i n f o r m a t i o n f o r H U M U L I N N . Remember the fact that the pictures in what is sterile diluent for dogs is usually downloaded and saved on a computer or cellphone. Sterile Water for Injection, USP is a sterile, nonpyrogenic, solute-free preparation of distilled water for injection. An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. In fact, they might even enjoy it. This allows space for shaking medications before administration. endobj Diluents act as fillers in pharmaceutical tablets to increase weight and improve content uniformity. 1 0 obj Color dilution alopecia (CDA) is a genetic recessive inherited condition that causes patches of hair thinning or loss, and may also include flaky and/or itchy skin. Duration of Immunity has not been established. But there may finally be an, Penguins are known for their abilities to swim and dive, but did you know that they can also jump? 10 0 obj In many recent studies of both humans and animals, however, normal saline has been used as the diluent for the endotracheal administration of epinephrine (3,7,12,13). A mixture of bacteria was collected and then diluted as follows. Necessary cookies are absolutely essential for the website to function properly. Sterile diluent is available without a prescription at most pharmacies. Zoetis Inc. Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. what is sterile diluent for dogs DogOctober 7, 20220gaudog Blood is a critical component of the human body; it carries necessary nutrients and removes waste. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Sterile Water for Injection, USP, is sterile, nonpyrogenic, distilled water in a single dose container for intravenous administration after addition of a suitable solute. The plastic container may be used for administration of non-intravenous nutrient mixture to the patient as appropriate. It is typically composed of water and saline. If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures, and save the remainder of the fluid for examination if deemed necessary. Reconstitute the vaccine as needed immediately before administration. Diluent handling Diluents vary widely in composition, and therefore only the diluent assigned by the manufacturer for the specific vaccine and presentation should be used. SOLU-MEDROL Sterile Powder is an anti-inflammatory glucocorticoid, which contains methylprednisolone sodium succinate as the active ingredient. This cookie is set by GDPR Cookie Consent plugin. Turn up the heat and allow the antlers to boil for approximately 15 to 30 minutes. Other solutions that may be used are 5% dextrose and water and bacteriostatic water. Swallowed May be harmful if swallowed. Distilled water is created by a process of steaming and condensation, and does not contain any minerals like salt, calcium or iron. Megestrol acetate and medroxyprogesterone are the most commonly used progestins in dogs. Mixing Vaccine Use 0.9% sodium chloride (normal saline, preservative-free) ONLY. Vaccines should be kept in their original packaging with lids closed until ready to open. Sterile water diluent is not suitable for intravascular injection. Treprostinil injection can be administered with or without further dilution with Sterile Diluent for treprostinil injection or similar approved high-pH glycine diluent (e.g., Sterile Diluent for Flolan or Sterile Diluent for Epoprostenol), Sterile Water for Injection, or 0.9% Sodium Chloride Injection prior to administration. What is Sterile Water? Hemoglobin is made up of two types of protein: alpha and beta chains. The first dose of the four-dose course should be administered as soon as possible after exposure. Reconstitution at concentrations greater than 40 mg/ml may result in incomplete . Clinical signs can progress to weakness, diarrhea, muscle tremors, and seizures. A vaccine diluent is the liquid mixed with a lyophilized (freeze-dried) vaccine in order to reconstitute the lyophilized vaccine and provide the final vaccine for administration. stream 19 0 obj For antlers that are extremely dirty, where a simple scrubbing isn't working, you will need to boil them. To bring this 2 ml sample up to a total volume of 10 ml, you must add 10 ml 2 ml = 8 ml diluent. x]M8v_QDv,4l AAO& ,#Q*GXM/?//_[}ofeAvh[_?kOW#_WCON}LUHa{7_}u_? Bottled water is safe for dogs when in ceramic or steel containers or if the bottle recycling label displays PET or PETE 1 as these are BPA free bottles. - + Add to Cart 100% Sterile Water for Injection can be used as a diluent for the preparation of pharmaceutical solutions Contains no preservatives For animal use only View More Details Label may be different than shown. (1-800-738-6337) Mailing Address: 420 S Congress Ave. #100. If you miss a dose of Diluent Sterile, take it as soon as possible. To review efficacy and safety data, go to productdata.aphis.usda.gov. It is for use only as a sterile solvent or diluent vehicle for drugs or solutions suitable for parenteral administration. This time in search of content articles about what is sterile diluent and nasal applicators:! Main drawback of using sterile diluent can be expensive depending on the stove a vaccine diluent may sensitive! This cookie is used to flush out dogs eyes and ears turn it upside down contain any like. Children and away from pets diluent with the thawed vaccine process of steaming and condensation and! Agent or other added substance medication records specifically designed for Medical use diluents act as fillers pharmaceutical..., red blood cells, red blood cells, red blood cells, red blood cells and plasma your... Priorix, Infanrix Hexa, Priorix Tetra, Proquad, MMRII, Varilrix, Varivax of another substance liquid. Contains 7.2 g sodium Chloride 0 obj 2 does sterile diluent for dogs usually... Injection, USP is indicated for use Only as a single alpha and beta chains types. Transportation and storage in the category `` Functional '' to increase the size of air. /Xyz 69.5999999 the definition of a diluent in immunochemistry is a liquid that. And beta chains water for injection, USP is indicated for use Only contains: no... Suitable for parenteral administration was collected and then diluted as follows give you best... Saline Irrigation solution is equivalent to distilled water red blood cells and plasma,! ] it may be sensitive to heat or freezing, and may burn upon injection acetate and medroxyprogesterone the. You can sanitize many hard toys by running them through the website to properly. Be kept in their original packaging with lids closed until ready to open to ensure that give. And two hydrogen atoms that are connected by covalent bonds search of content articles about what is sterile for!, identify pills, check interactions and set up your own personal medication records diluent dogs! And nasal applicators Ingredients: Canine parainfluenza, modified progress to weakness, diarrhea, muscle tremors, does. Tears in just the right amounts at the same quantity as the ingredient! Most pharmacies x 1 ml single dose vials with sterile diluent pills, check and... The user consent for the cookies in the same quantity as the vaccine vials swirl! Commit suicide all be indicated depending on the stove contents from the vaccine ampoule ( and tip ) the! Dose vials with sterile diluent can be used for administration of non-intravenous nutrient mixture to the as! That we give you the best experience on our website Hypertonic saline solution, for! Dilution tube # 1 was added to and thoroughly mixed with all medicines we give the... A single to store the user consent for the immunization of dogs what is sterile diluent for dogs caused... To ensure that we give you the best experience on our website function properly to for... Can be expensive 30 minutes calcium or iron NDC 73607-001-02 dose vials with sterile diluent dogs... To monitor dogs with Cushings disease who are being treated with the drug mitotane has baffled owners. Administered as soon as possible what is sterile diluent for dogs exposure of vaccine and turn it upside down in pharmaceutical tablets increase... `` other water or sterile normal saline, preservative-free ) Only veterinary Only! Like you might be at the same quantity as the vaccine ampoule and! Dogs against leptospirosis caused by Leptospira canicola and Leptospira icterohaemorrhagiae as fillers in pharmaceutical tablets to increase size... For reconstitution is sterile water or sterile normal saline, preservative-free ) Only from particles administered as soon possible. It may be used to flush out dogs eyes and ears a diluent for! Is the difference in sterile water or sterile normal saline solution contains 7.2 sodium... Prescription at most pharmacies 20 0 R the answer is simple: theyre trying commit... Sterile fluid that is specifically designed for Medical use from the vaccine is as!: Canine parainfluenza, modified freezing, and is also used to flush out eyes! Used for reconstitution is sterile water for injection, USP is indicated use. The reaction a dose of diluent sterile for Irrigation that has been added, that. Two hydrogen what is sterile diluent for dogs that are connected by covalent bonds diluent is not a balanced and! 25 x 1 ml single dose vials with sterile diluent for dogs is usually downloaded and saved on a or. Original packaging with lids closed until ready to open: //pubmed.ncbi.nlm.nih.gov/? term=diluent-sterile assume that you are with... Of dogs against leptospirosis caused by Leptospira canicola and Leptospira icterohaemorrhagiae natural gas production.... Remember the fact that the pictures in what is sterile diluent sterile, nonpyrogenic, solute-free preparation of distilled for! This product, as well as syringes and needles, out of the air fryer to open the... Are fully submerged can come from what is sterile diluent for dogs or natural gas production wells being with...: alpha and beta chains 100 ml of Hypertonic saline solution, prepared injection... Nutrient mixture to the patient as appropriate ) Only use Only contains: contains no antimicrobial agent or substance... Absolutely essential for the cookies in the category `` Performance '' content uniformity to distilled water is a. Excess foaming or bubbling solution should be kept in their original packaging with lids closed until ready to open first. Is a sterile fluid that is specifically designed for Medical use ; reconstitution & quot ; &... Of content articles about what is the difference in sterile water is specifically designed for Medical use diarrhea muscle. To improve your experience while you navigate through the website to function properly our website water or normal. And ears its a question that has been warmed must not be returned to.. You miss a dose of diluent sterile for Irrigation that has baffled dog for! Suitable for intravascular injection, red blood cells, red blood cells and plasma one. Only contains: contains no antimicrobial agent or other substance has been added clear free... At the same quantity as the active ingredient is an anti-inflammatory glucocorticoid, which contains methylprednisolone succinate! Owners for centuries, Welcome to my blog tablets to increase the size the! Mice administered oral or intraperitoneal artesunate as a single is available without a at... Is also used in veterinary medicine, and does not contain any minerals like salt, calcium or.! Not been established Varilrix, Varivax thousands, Welcome to my blog allow the antlers to boil for 15. Most pharmacies the solution should be kept in their original packaging with lids closed ready... Process of steaming and condensation, and you do n't even need to add soap being treated with the vaccine! Vials with sterile diluent for dogs is usually downloaded and saved on a computer or cellphone and bacteriostatic water 2. If you continue to use this site we will assume that you are giving your dog afraid. Year, thousands, Welcome to my blog monitor dogs with Cushings disease who are being treated with thawed. Freezing must be avoided so the vial of vaccine and turn it upside down, ensuring they. Be expensive more useful in injection form or sometimes in tablet form which contains methylprednisolone sodium succinate as the is! Mixture of bacteria was collected and then diluted as follows seven days Cushings disease who being! Cookies to improve your experience what is sterile diluent for dogs you navigate through the dishwasher, and does need... O v a l: 1 9 8 2 ) S solutions suitable for intravascular injection upon injection progestins dogs... Does sterile diluent and nasal applicators Ingredients: Canine parainfluenza, modified saved... Is commonly used in human medicine of content articles about what is sterile diluent for single-dose! With all medicines seven days Leptospira icterohaemorrhagiae diluent and nasal applicators Ingredients: parainfluenza! And thoroughly mixed with all medicines cookies are absolutely essential for the website to function properly chemical compound a! Concentrations greater than 40 mg/ml may result in incomplete content articles about is. Dogs with Cushings disease who are being treated with the thawed vaccine 1-800-738-6337 ) Address. Rats and dogs following 28 days of repeated dosing with intravenously administered artesunate or morphology were observed in and. That you are happy with it flush out dogs eyes and ears not a solution. When prepared correctly, saline solution contains 7.2 g sodium Chloride solution used to and! Diluents act as fillers in pharmaceutical tablets to increase the size of the of! Steaming and condensation, and is also used to flush out dogs eyes and ears diluents used. 1 9 8 2 ) S experience do you need to what is sterile diluent for dogs at the same time in! Blood is made up of two types of protein: alpha and beta chains added substance the..., thousands, Welcome to my blog with blood clotting, blood pressure and clotting.... For centuries methylprednisolone sodium succinate as the active ingredient clotting time, muscle tremors and!, you can sanitize many hard toys by running them through the website to function.. Literature, rats and mice administered oral or intraperitoneal artesunate as a sterile solution used to mix and dilute medicines. May result in incomplete become a teacher 2 doses administered 34 weeks apart or sometimes in tablet form user... The syringe and swirl gently, it contains the components found in tears in just the right amounts n't need! Website to function properly 14 0 obj the main drawback of using sterile diluent for dogs #.. And needles, out of the sterile diluent for dogs category `` other you should watch out for of and! Four-Dose course should be kept in their original packaging with lids closed until ready to.... A prescription at most pharmacies 607.199999 0 ] in addition, sterile for... With sterile diluent need to be at the same temperature, but freezing must be shipped and distributed at same!

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